SYSTEMIC definition: 1. A systemic drug, disease, or poison reaches and has an effect on the whole of a body or a plant…. Learn more. 1. of or pertaining to a system. 2. pertaining to, affecting, or circulating through the entire body: systemic disease; systemic pesticide. The adjective systemic is often used to describe diseases or disorders; a systemic illness affects your whole body or an entire system — like your digestive system. SYSTEMIC definition: of or relating to a system, especially when affecting the entirety of a thing. See examples of systemic used in a sentence. “Systemic” means affecting the entire body rather than a single spot. In medicine, a systemic condition, treatment, or reaction is one that travels through your bloodstream and reaches tissues and organs throughout your body, as opposed to staying in one localized area. Systemic – born out of a deep desire to bring our vision to life, to create something authentic and to craft pieces that embody timelessness and individuality. Systematic and systemic both come from system. Systematic is the more common word; it most often describes something that is done according to a system or method. Systemic describes what relates to or affects an entire system, be that system physical, organizational, or societal. Systemic refers to something that is prevalent throughout or affecting the whole system or body. It can be used in various contexts like biology, medicine, sociology, or politics, indicating a widespread issue or condition impacting an entire organism, organization, or society, rather than isolated parts. In simplest terms, something described as systematic uses or follows a system, while something described as systemic is part of, or is embedded in, the system itself. This disambiguation page lists articles associated with the title Systemic. If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article.